If you want to search and replace paths in multiple locations use Windows -> Hscript Textport window

and write:

opchange \$DOWNLOADS"/wetransfer" \$JOB"/geo"

Backslash before variables will allow you to keep variables ($JOB and $DOWNLOADS in this case) and not expand them to full path.

Another case: you imported FBX with materials. You can move them to mat context and change path with this:

opchange ../../materials /mat

Documentation:
https://www.sidefx.com/docs/houdini/commands/opchange.html